- Editorial
- Cardiology
- Coronavirus disease 2019 and mRNA vaccines: what’s next – miRNA?
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Joon Kee Lee, Heon-Seok Han
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Clin Exp Pediatr. 2022;65(6):302-303. Published online March 28, 2022
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MicroRNAs (miRNAs) are small single-stranded noncoding RNA molecules that function in RNA silencing and the posttranscriptional regulation of gene expression. The potential role of miRNAs as biomarkers of myocarditis is promising, and miRNAs are expected to be utilized in various clinical fields in the future. |
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- Case Report
- Atypical presentation of Kawasaki disease resembling a retropharyngeal abscess
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Eu Jin Kim, Young Su Lim, Ji Eun Yoon, Heon-Seok Han
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Clin Exp Pediatr. 2009;52(2):251-255. Published online February 15, 2009
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Kawasaki disease is an acute systemic inflammatory disorder, the etiology of which has not yet been established. The clinical manifestations are non-specific and are common to many pediatric infectious and immunologic diseases. In 2 cases presenting fever, cervical lymphadenopathy, and retropharyngeal abscess-like lesions on the neck shown in a computerized tomography (CT) scan, the diagnosis of Kawasaki disease was delayed.... |
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- Original Article
- Effect of GnRH analogue on the bone mineral density of precocious or early pubertal girls
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Jeong Sook Lim, Heon-Seok Han
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Clin Exp Pediatr. 2009;52(12):1370-1376. Published online December 15, 2009
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Purpose : Treatment of precocity with gonadotropin releasing hormone analogue (GnRHa) might theoretically exert a detrimental effect on the bone mass during pubertal development. We investigated the short-term changes in bone mineral density (BMD) during GnRHa treatment and the enhancement in the changes with the co-administration of GnRHa and human growth hormone (hGH).
Methods : Forty girls with precocious or... |
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- Effects of soy-based formula on infants` growth and blood laboratory values spanning 3 years after birth
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Ji Eun Yoon, Mi-Jung Kim, Heon-Seok Han
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Clin Exp Pediatr. 2009;52(1):28-35. Published online January 15, 2009
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Purpose : We compared body growth, blood cell counts, and chemistry among infants receiving soy-based formula (SF), breast milk (BM), and casein-based formula (CF).
Methods : Full-term neonates delivered at our hospital from June 2001 to August 2003 were recruited and divided into 3 feeding groups (BM=20, SF=19, CF=12) according to the parents wishes. Breast feeding or artificial formulae were... |
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- Umbilical venous line-related pleural and pericardial effusion causing cardiac tamponade in a premature neonate : A case report
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Eun Jeong Hong, Kyung A Lee, Il-Heon Bae, Mi-Jung Kim, Heon-Seok Han
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Clin Exp Pediatr. 2006;49(6):686-690. Published online June 15, 2006
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Cardiac tamponade with pleural and pericardial effusion is a rare but life-threatening complication of umbilical venous catheterization in the newborn. It requires a timely diagnosis and urgent treatment, such as pericardiocentesis, to save lives of affected patients. Recently, we experienced a 7 day-old, very low birth weight infant, who developed a cardiac tamponade with pleural and pericardial effusions complicated by... |
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- Effect of GnRH analogue on predicted adult height in girls with early puberty
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Byung-Hoon Ahn, Heon-Seok Han
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Clin Exp Pediatr. 2006;49(5):552-557. Published online May 15, 2006
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Purpose : The recent results observed in precocious puberty and the hope that interrupting puberty might increase adult height have led to an attempt to use GnRH agonist(GnRHa) in children with premature puberty and a poor growth prognosis. We aimed to analyze the growth promoting effect of GnRHa in girls with early puberty and low predicted adult height(PAH).
Methods : Thirty... |
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- Clinical Characteristics in Patients with Kawasaki Disease Who
Received Intravenous Gamma-globulin Retreatment
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Deok-Soo Kim, Yoon-Soo Hahn, Heon-Seok Han
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Clin Exp Pediatr. 2002;45(11):1411-1416. Published online November 15, 2002
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Purpose : Although the use of intravenous gamma-globulin(IVGG) in Kawasaki disease(KD) is effective in reducing clinical symptoms and coronary artery complications, 20-30% of patients have persistent or recrudescent fever and ongoing clinical symptoms. In these patients, the additional infusion of IVGG is considered. The authors studied the characteristics of patients who received IVGG retreatment, and compared them with the patients... |
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- Effect of Hypoxia on Antegrade and Retrograde Atrioventricular Conduction in Isolated Perfused Rabbit Heart
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Heon-Seok Han, Young Jun Song, Miran Kang
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Clin Exp Pediatr. 2000;43(9):1213-1223. Published online September 15, 2000
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Purpose : Cyanotic congenital heart diseases patients are in a state of hypoxia since birth. In general, hypoxia delays atrioventricular conduction. The atrioventricular node in such a hypoxic condition would have a different function, and some possibility for arrhythmia. The authors studied atrioventricular nodal function during hypoxia to elucidate the relationship between hypoxia and arrhythmia, including atrioventricular node in terms... |
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- Changes of Peripheral IFN-γ-Producing CD4(+) and CD4(-) Cell Frequencies in Kawasaki Disease
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Joung-Min Eom, Heon-Seok Han, Youn-Soo Hahn
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Clin Exp Pediatr. 2000;43(10):1350-1355. Published online October 15, 2000
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Purpose : This study was performed to analyze the frequencies of peripheral IFN-γ-producing cells at the single cell level, and to determine concentrations of circulating interferon-γ(IFN-γ) in the acute and subacute phases of Kawasaki disease(KD).
Methods : Ten patients with KD were studied and seven healthy children were selected as control subjects. Using immunofluorescent detection of intracellular IFN-γ in CD4(+) and... |
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- Age-Related Criteria for Signal-Averaged Electrocardiographic Late Potentials in Children
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Heon-Seok Han, Ki-Moon Cha
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Clin Exp Pediatr. 1999;42(5):679-685. Published online May 15, 1999
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Purpose : Ventricular late potentials have been shown to predict malignant ventricular arrhythmia and sudden cardiac death in patients with myocardial infarction and cardiomyopathy. Low amplitude and high frequency potentials at the end of the QRS complex can be detected on the body surface using signal-averaged electrocardiogram(SAECG). This study determines the age-related criteria of SAECG parameters and age-related differences.
Methods :... |
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- Original Article
- Nonoperative Treatment of PDA Using the Duct-OccludⓇ
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Dong Woon Shin, Kyung Hee Lee, Heon-Seok Han
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Clin Exp Pediatr. 1997;40(5):635-640. Published online May 15, 1997
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Purpose : Among the several transcatheter devices of PDA occlusion, Rashikind device was the most extensively experienced, but it had risk of occluder embolism and incomplete occlusion of PDA, approximately 27%. The authors used Duct-OccludⓇ, made of 0.028 inch stainless steel coil. The coil is double cone-shape in released state, and used in streched condition through 4F implantation catheter for... |
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